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Key antioxidant mechanisms (Figure 3) of flavonoids include the following: (1) Direct ROS scavenging: Flavonoid molecules, especially those with an ortho-dihydroxy structure in the B ring, a 2,3-double bond conjugated with a 4-oxo group in the C ring, and hydroxyl groups at positions 3 and 5, are highly effective at scavenging radicals [61]